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Source document· December 7, 2025

Constructing your 2026 portfolio: 5 investing checklist to-do's

View original at finance.yahoo.com
Constructing your 2026 portfolio: 5 investing checklist to-do's Yahoo Finance Markets and Data Editor Jared Blikre and Slatestone Wealth chief market strategist Kenny Polcari take a look at market (^DJI, ^GSPC, ^IXIC) and sector action year to date to examine how investors should be constructing their 2026 portfolios…
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  • There is massive energy demand, not waning demand

    80% confidence
  • Market loves gridlock because it's predictable

    80% confidence
  • IBM is a leader in quantum computing space

    80% confidence
  • Democrats expected to retake House, Republicans to maintain Senate in 2026

    80% confidence
  • Risk is the only thing you can control in investing

    80% confidence
  • XLE energy sector ETF is ready to break out

    80% confidence
  • Fed funds rate will be in 3.5-3.75% range after December meeting

    80% confidence
  • AI is not in a bubble, though valuations are stretched

    80% confidence
  • Fed should not cut rates further, current levels are historically normal

    80% confidence
  • Market could see 10-15% decline in 2026 midterm year

    80% confidence
  • Healthcare sector will attract money in 2026

    80% confidence
  • 2026 is a mid-term year that could bring chaos, confusion, and volatility

    80% confidence
  • Financials will be a strong sector in 2026

    80% confidence
  • Market expectations at start of 2025 were 8-12% total return

    80% confidence

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Q4 2026 Oncology Data Season and Biotech Capital Allocation: ESMO Readouts, Ivonescimab PDUFA, and Diverging Corporate Moves
Late-2026 biotech is driven by a dense catalyst calendar. ESMO 2026 delivers data from ivonescimab, Enhertu, R-DXd and bemarituzumab, and the FDA has set a 14 Nov PDUFA date for the ivonescimab BLA. Capital allocation is diverging. Krystal Biotech authorized a $400M buyback while lowering FY2026 spend guidance and pushing milestones into 2027. Spago is moving to delist from Nasdaq First North. The facts are clinical and corporate events, not AI or fintech, so the finance angle is limited to capital markets (buybacks, guidance, delistings, regulatory timelines).
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EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
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Donde las fuentes discrepan
Ford Motor Company
Both facts give cash for Ford Motor Company at the same point in time (2025-12-31; FY 2025 year-end and Q4 2025 year-end are the same date). Both are labelled USD, but the values are 23,356,000,000 and 23.356, which cannot both be true in USD. The two numbers agree once the second is read as billions (23.356 bn = 23,356,000,000), so the economic content is consistent and the conflict is a unit/scale error in the Q4 2025 record. The period is not the reason for the conflict: a Q4 and an FY figure at the same year-end date should match.
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