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News articleYahoo Finance· October 8, 2026

Bristol Myers Squibb Announces ZENBEXUSTM (iberdomide) in Combination with Daratumumab and Dexamethasone (ZDd) Demonstrates Superior Progression-Free Survival vs. Standard of Care in Relapsed and Refractory Multiple Myeloma in Phase 3...

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Bristol Myers Squibb Announces ZENBEXUSTM (iberdomide) in Combination with Daratumumab and Dexamethasone (ZDd) Demonstrates Superior Progression-Free Survival vs…
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  • ZENBEXUS is an effective oral treatment option that can be easily used in diverse care settings, including community settings.

    60% confidence

  • The safety profile of ZENBEXUS in combination with standard therapies remained consistent with previously reported safety findings from the study.

    60% confidence

  • ZDd demonstrated a statistically significant improvement in PFS vs DVd in EXCALIBER-RRMM: median PFS 42 vs 20 months, HR 0.49, p<0.000001, a 51% reduction in risk of progression or death.

    60% confidence

  • EXCALIBER-RRMM results reinforce the clinical value of ZENBEXUS with daratumumab and dexamethasone; MRD negativity benefit translated into meaningful PFS improvement.

    60% confidence

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